UW-NEXTGEN Profile
PGRN Network Resource: Next Generation Sequencing
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PGRN Projects Funded Through the DSR
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Abstract (Updated, October 2011)
The genetic architecture affecting drug adsorption, distribution, metabolism, excretion and toxicity (ADMET) is complex and is known to include both common and rare variants. Although genome-wide association studies (GWAS) can evaluate the role of common variants, rare variants are currently more difficult to identify. The development and application of second-generation sequencing is rapidly changing our ability to explore targeted resequencing and expression analysis in humans. The overall goal of this PGRN resource is to provide next generation sequencing to help explore associations with drug responses.
Team Members
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Debbie Nickerson, Ph.D. Principal Investigator;Professor Email: debnick@uw.edu Phone: (206) 685-7387 |
Mark Rieder, Ph.D. Co-Investigator; Research Professor Email: mrieder@uw.edu Phone: (206) 221-4195 |
Joshua Smith Lead Analyst Email: jds66@uw.edu Phone: (206) 616-1020 |
Peggy Robertson Research Scientist Email: pdr@uw.edu Phone: (206) 221-4530 |
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Dana Seaman Project Manager Email: dseaman@uw.edu Phone: (206) 543-6229 |
Christa Poel Research Scientist/Sample Coordinator Email: cbroers@uw.edu Phone: (206) 221-6439 |