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Last updated November 3, 2014                                              Read More  

 

UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in European and African American smokers. Cancer Epidemiol Biomarkers. PMID: 25277794.

Genome-wide discovery of drug-dependent human liver regulatory elements. PLoS Genet. PMID: 25275310.

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet. PMID: 25262344.

The evolution of novelty in conserved genes; evidence of positive selection in the Drosophila fruitless gene is localised to alternatively spliced exons. Heredity (Edinb). PMID: 24149653.

Applied pharmacogenomics in cardiovascular medicine. Annu Rev Med. PMID: 24111889.

Further Investigation in Europeans of Susceptibility Variants for Polycystic Ovary Syndrome Discovered in Genome-wide Association Studies of Chinese Individuals. J Clin Endocrinol Metab. PMID: 25303487.

Genetic variation in the HLA region is associated with susceptibility to herpes zoster. Genes Immun. PMID: 25297839.

Pharmacogenomics in Asthma Therapy: Where Are We and Where Do We Go? Annu Rev Pharmacol Toxicol. PMID: 25292431.

Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five United States Medical Centers. Annu Rev Pharmacol Toxicol. PMID: 25292429.

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate. Transl Psychiatry. PMID: 25290263.

Is personalized medicine achievable in obstetrics? Semin Perinatol. PMID: 25282474.

Warfarin pharmacogenetics. Trends Cardiovasc Med. PMID: 25282448.

Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. PMID: 25282103.

Metformin pharmacogenomics: biomarkers to mechanisms. Diabetes. PMID: 25060891.

Metformin pharmacogenomics: current status and future directions. Diabetes. PMID: 25060887.

PharmGKB summary: very important pharmacogene information for UGT1A1. Pharmacogenet Genomics. PMID: 24492252.

Using systems approaches to address challenges for clinical implementation of pharmacogenomics. Wiley Interdiscip Rev Syst Biol Med. PMID: 24319008.

A Call for Accurate Pharmacogenetic Labeling: Telling It Like It Is. JAMA Intern Med. PMID: 25317574.

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation. Genome Biol. PMID: 25316374.

Mangravite et al. reply. Nature. PMID: 25230670.

HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies. Blood. PMID: 24970932.

Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. PMID: 24853734.

Prerequisites to implementing a pharmacogenomics program in a large health-care system. Clin Pharmacol Ther. PMID: 24807457.

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. PLoS One. PMID: 24520335.

Unmet needs in preventing adverse drug-drug interactions. Clin Adv Hematol Oncol. PMID: 24518424.

Statin-induced changes in gene expression in EBV-transformed and native B-cells. Hum Mol Genet. PMID: 24179175.

Regulatory Polymorphisms in Human DBH Affect Peripheral Gene Expression and Sympathetic Activity. Circ Res. PMID: 25326128.

The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness. Acad Emerg Med. PMID: 25156930.

Genetic influence on exercise-induced changes in physical function among mobility-limited older adults. Physiol Genomics. PMID: 24423970.

Last updated October 25, 2014                                     More Publications  

 

Upcoming

December 12, 2014  RIPS Seminar. Speaker: TBD, Group: P-STAR.

January 9, 2015RIPS Seminar. Speaker: TBD, Group: PHONT.

February 13, 2015RIPS Seminar. Speaker: TBD, Group: PAAR.

March 13, 2015RIPS Seminar. Speaker: TBD, Group: PAPI-2.