Interpreting the CYP2D6 Results From the International Tamoxifen Pharmacogenetics Consortium. Clin Pharmacol Ther. PMID: 25056393.
Metformin pharmacogenomics: current status and future directions. Diabetes. PMID: 25060887.
Metformin pharmacogenomics: biomarkers to mechanisms. Diabetes. PMID: 25060891.
Size matters: How population size influences genotype-phenotype association studies in anonymized data. J Biomed Inform. PMID: 25038554.
CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort. Pharmacogenet Genomics. PMID: 25051018.
Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality. J Am Med Inform Assoc. PMID: 25053577.
Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. Clin Pharmacol Ther. PMID: 25054431.
Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability. CPT Pharmacometrics Syst Pharmacol. PMID: 25029353.
(Epi)Genetic Analyses of Age-Related Macular Degeneration: Case-Control and Discordant Twin Studies. Hum Hered. PMID: 25033836.
Genetic variants in the complement system predisposing to age-related macular degeneration: A review. Mol Immunol. PMID: 25034031.
Comparative effectiveness of next generation genomic sequencing for disease diagnosis: Design of a randomized controlled trial in patients with colorectal cancer/polyposis syndromes. Contemp Clin Trials. PMID: 24997220.
Knowledge boosting: a graph-based integration approach with multi-omics data and genomic knowledge for cancer clinical outcome prediction. J Am Med Inform Assoc. PMID: 25002459.
Establishment of CYP2D6 reference samples by multiple validated genotyping platforms. Pharmacogenomics J. PMID: 24980783.
A Genome-Wide Association Study to Identify Genomic Modulators of Rate Control Therapy in Patients With Atrial Fibrillation. Am J Cardiol. PMID: 25015694.
Genetic risk factors for major bleeding in patients treated with warfarin in a community setting. Clin Pharmacol Ther. PMID: 24503627.
Integrating systems biology sources illuminates drug action. Clin Pharmacol Ther. PMID: 24577151.
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for ivacaftor therapy in the context of CFTR genotype. Clin Pharmacol Ther. PMID: 24598717.
Nicotine Pharmacokinetics in Rats is altered as a function of Age, impacting the Interpretation of Animal Model Data. Drug Metab Dispos. PMID: 24980255.
Clinical decisions. Screening an asymptomatic person for genetic risk. N Engl J Med. PMID: 24941182.
Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability. Endocrinology. PMID: 24641623.
eMERGEing progress in genomics-the first seven years. Front Genet. PMID: 24987407.
Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. PMID: 23716066.
The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function. J Clin Endocrinol Metab. PMID: 24471563.
Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. PMID: 24981077.
Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA. J Natl Cancer Inst. PMID: 24700804.
PharmGKB summary: ifosfamide pathways, pharmacokinetics and pharmacodynamics. Pharmacogenet Genomics. PMID: 24401834.
Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo. Pharmacogenet Genomics. PMID: 24305170.
A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469. Pharmacogenet Genomics. PMID: 24300566.
Fast pairwise IBD association testing in genome-wide association studies. Bioinformatics. PMID: 24158599.
PharmGKB summary: mycophenolic acid pathway. Pharmacogenet Genomics. PMID: 24220207.
PharmGKB summary: venlafaxine pathway. Pharmacogenet Genomics. PMID: 24128936.
Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study. Clin Cancer Res. PMID: 24084763.